Objectives: To detect cutaneous drug reactions through spontaneous reporting system in IGGMCand H, Nagpur and analyze them using standard assessment luau thank you cards scales.Materials and Methods: An observational, prospective study was performed in patients attending dermatology OPD of IGGMC and H, Nagpur from 1 st June 05 to 31 st May 09.Patients were examined for cutaneous drug reactions (CDRs) by spontaneous Adverse Drug Reaction reporting system.
Results: Among 2693 total ADRs reported, 872 (33.04%) were CDRs.Antimicrobials (55.
5%) were the main drugs involved followed by NSAIDs (18.56%) and steroids (12.61%).
Maculopapular rash (37.73%) followed by fixed drug eruption (17.2%) and urticaria (14.
56%) were the most frequently observed CDRs.The common drugs causing CDRs were turbo air m3f72-3-n cotrimoxazole (20.41%), topical steroids (betamethasone), ibuprofen (7.
91%), ampicillin (6.54%), diclofenac (4.7%) and iron dextran (3.
44%).Conclusion : It was observed that commonly used drugs like antibiotics and NSAIDs lead to maximum number of CDRs.Hence strict vigilance is required while using them.
This study provides a database of ADRs due to common drugs, which will help clinicians in safe use of these drugs.